Recent Documents


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Principal Investigators

Thanks to all Participating Centers and collaborators for engaging in this research program!

Thanks to the CCCTG for endorsing this research project.

Thanks to the CNTRP for their precious contribution.

Study Team Leaders

Dr. Maureen O. Meade

Maureen O. Meade is a critical care consultant at Hamilton Health Science and a professor of Medicine at McMaster University, Canada.  A senior clinical investigator of the Canadian Critical Care Trials Group, she has spearheaded 5 randomized controlled trials in lung protective ventilation strategies for ARDS, including the international Lung Open Ventilation Study of higher vs lower PEEP (JAMA 2007) and the international OSCILLATE trial of high frequency oscillation (NEJM 2013).  Dr. Meade’s research has advanced clinical practice, with results that have impacted recommendations on UptoDate and recent ARDS management guidelines (AJRCCM 2017).

Dr. Meade is Director of the DONATE Research Program, which she launched together with Dr. D’Aragon in 2015.  Their primary objective is to build a national platform for clinical trials in donation science - the intensive care management of deceased organ donors. This platform currently consists of the national cohort study (Canada-DONATE), qualitative research, surveys, feasibility studies and knowledge translation initiatives, to which pilot RCTs and pragmatic, national RCTs will be added in the future.  The recipient of local and national research mentorship awards, Dr. Meade’s aim is to foster junior investigators and research trainees in leadership roles on every project of this national collaboration.

Dr. Frédérick D’Aragon

Frédérick D’Aragon, MD, MSc (Epid), MSc (TPM), FRCPC is an Assistant Professor in the Departments of Anesthesiology and Critical Care at the Centre Hospitalier Universitaire de Sherbrooke (CHUS), Quebec.  He is a junior investigator and recently obtained a Fonds de Recherche en Santé-Québec Career Award J1.  Dr D’Aragon has a unique expertise; in addition to his clinical training in anesthesiology and critical medicine, he holds 2 master degrees: one in Health Research Methodology (McMaster University) and the other in Transplantation Medicine (University of Barcelona).
Dr D’Aragon is co-leading the Canada-DONATE National Cohort Study which aims to describe the management of organ donors across Canada. The results of this study will assess prognostic factors associated with increased organ recovery and will also overcome research barriers and build a national research platform to support clinical trials in organ donation.

Dr. Simon Oczkowski

Dr. Oczkowski is a critical care physician at Hamilton Health Sciences and an assistant professor in the Department of Medicine at McMaster University. He holds a master’s degree in bioethics from the University of Toronto and is completing his masters of science in clinical epidemiology at McMaster University. His research interests include ethics and end of life care, including organ donation. He is leadingthe Canada-DONATE qualitative study, a mixed-methods project which aims to describe the complex process of organ donation in the intensive care unit. This project will identify key barriers and facilitators to the practice of organ donation and identify ways to improve the process of organ donor care in the ICU.

Farid Foroutan

Farid is a PhD candidate at McMaster university under the supervision of  Dr. Maureen O. Meade and Dr. Gordon Guyatt. He is working with the DONATE Canada team to develop a generic graft outcome measurement tool to be used in future trials aimed at identifying the best management strategies for deceased donors. Farid also is part of the heart failure and cardiac transplant team at Toronto General Hospital. In his spare time, Farid loves to spend time exploring the outdoors (challenging and extreme conditions), and participating in endurance sports.

Dr. Samantha Arora

Dr. Samantha Arora is a critical care physician at the Northern Ontario School of Medicine. She is completing her master’s of science in health research methodology at McMaster University, supported in part through a research fellowship from McMaster’s Clinician Investigator Program. Her interests include end of life care and organ donation. Dr. Arora is leading a knowledge translation initiative of DONATE known as Evidence Bulletins, whereby literature relevant to important donation practices are reviewed and systematically appraised or meta-analyzed. Recommendations and clinical pearls are accessibly summarized on rapid-review cards for clinicians to use at the bedside.